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There is currently no cure for HIV and vaccine development has proved challenging. Patients are able to manage their disease with the use of highly active antiretroviral therapy (HAART), which has had a positive impact on reducing HIV morbidity and mortality. As with HIV infection in humans, infection with Simian Immunodeficiency Virus (SIV) in rhesus macaques is lifelong due to infected cells that lie dormant in the DNA of the virus that is integrated into the host DNA.

Texas Biomedical Research Institute
Luis Giavedoni; Zhao Lai

The purpose of this study is to evaluate the effect of LCZ696 compared to valsartan in the reduction of cardiovascular death and heart failure(HF) hospitalizations in patients with HF with preserved ejection fraction.

Brooke Army Medical Center
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